| Title |
Racionalaus antibakterinių vaistų vartojimo algoritmo įtaka Staphylococcus aureus atsparumo antibiotikams kitimui / |
| Translation of Title |
Rational application algorithm of antibacterial drugs to Staphylococcus aureus resistance. |
| Authors |
Bagdonas, Rokas ; Tamelis, Algimantas ; Rimdeika, Rytis ; Kiudelis, Mindaugas ; Jankūnas, Vytautas |
| DOI |
10.15388/LietChirur.2006.1.2283 |
| Full Text |
|
| Is Part of |
Lietuvos chirurgija = Lithuanian surgery.. Vilnius : Vilniaus universiteto leidykla. 2006, t. 4, Nr. 1, p. 54-58.. ISSN 1392-0995. eISSN 1648-9942 |
| Keywords [eng] |
Staphilococcus aureus ; resistance to antibiotics ; racional antibioticotherapy |
| Abstract [eng] |
Background / objective. The major challenge for burn team is infection which is known to cause over 50% of burn deaths. Burns become infected because the environment at the site of the wound is ideal for the propagation of the infecting organism. The aim of the study was to evaluate the rational application algorithm of antibacterial drugs to influence the S. aureus resistance changes to antibiotics. Patients and methods In 2001, the Rational Application Algorithm of antibacterial drugs was introduced into the Plastic Surgery and Burns Department. Performing the perspective analysis, we investigated Staphylococcus aureus resistance and its dynamics to antibacterial drugs using the computerized database of the Microbiology Laboratory in KMUH in 2001–2002. Analyzing a retrospective group (2000) and a perspective one (2001–2002) we compared changes of Staphylococcus aureus resistance to ciprofloxacin, gentamicin, erythromycin, fucidin, clindamycin, oxacillin, penicillin, rifampicin, tetracycline and vancomycin. Results. S. aureus resistance to antibiotics decreased after introducing the Rational Application Algorithm of antibacterial drugs. The difference is statistically insignificant. The resistance of this microorganism decreased slightly to erythromycin and statistically significantly to penicillin. Conclusions The Rational Application Algorithm of antibacterial drugs allows to reduce and control S. aureus resistance to antibacterial drugs. S. aureus resistance to erythromycin and penicillin decreased statistically significant after introducing the Rational Application Algorithm of antibacterial drugs into clinical practice. |
| Published |
Vilnius : Vilniaus universiteto leidykla |
| Type |
Journal article |
| Language |
Lithuanian |
| Publication date |
2006 |
| CC license |
|
