Title Fluorescence diagnostics of oral cancer
Another Title Burnaryklės navikų intraarterinė fluorescencinė diagnostika.
Authors Bloznelytė-Plėšnienė, Laima ; Mordas, Aleksandras ; Čepulis, Vytautas ; Venius, Jonas ; Liutkevičiūtė-Navickienė, Jurgita ; Rutkovskienė, Laimutė ; Ostapenko, Valerijus ; Valuckas, Konstantinas Povilas
DOI 10.6001/actamedica.v18i2.1817
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Is Part of Acta medica Lituanica.. Vilnius : Vilniaus universiteto leidykla. 2011, vol. 18, no. 2, p. 63-69.. ISSN 1392-0138. eISSN 2029-4174
Keywords [eng] fluorescence diagnostics ; oral cancer ; intra-arterial
Abstract [eng] The visual fluorescence diagnostics and spectroscopic measurements of healthy mucosa were performed for these volunteers. Results. A specific pink fluorescence of malignant tissue was noted while illuminating a tumour with violet light. The margins of fluorescence usually coincided with those of a malignant tumour. In doubtful cases, biopsy and morphological examination of the tissue were performed. All malignant tumours, except melanoma, showed a specific pink fluorescence when illuminated with violet light, and no fluorescence was noted in normal mucosa. However, in some cases glow artefacts were observed. We identified these "glow artefacts" - a nonspecific lilac fluorescence - in the healthy mucosa of 20 patients (in 6 patients from the first group and in 14 from the second group). Usually, artefactual fluorescence was noted in the gums (in 18 patients from 20) and at the basis of the tongue (in 11 patients from 20). There was no artefactual fluorescence in 7 patients who underwent I/a FD. Conclusions. Fluorescence diagnostics is useful for early detection of primary and recurrent malignant oral tumours, except melanoma. However, an artefactual fluorescence in the gums or in the basis of the tongue can appear. I/a FD allows avoiding this artefactual fluorescence.
Published Vilnius : Vilniaus universiteto leidykla
Type Journal article
Language English
Publication date 2011
CC license CC license description