| Title |
Išplitusio sensibilizuoto krūties vėžio diagnostika ir gydymas |
| Translation of Title |
Sensitized treatment and diagnostics of advanced breast cancer. |
| Authors |
Bloznelytė-Plėšnienė, Laima ; Sendiulienė, Daiva ; Liutkevičiūtė-Navickienė, Jurgita ; Rutkovskienė, Laimutė ; Ostapenko, Valerijus ; Samalavičius, Narimantas Evaldas |
| DOI |
10.15388/LietChirur.2011.1.2077 |
| Full Text |
|
| Is Part of |
Lietuvos chirurgija.. Vilnius : Vilniaus universiteto leidykla. 2011, t. 9, Nr. 3-4, p. 64-73.. ISSN 1392-0995. eISSN 1648-9942 |
| Keywords [eng] |
Advanced breast cancer ; Radiosensitized treatment ; Hematoporphyrin derivative |
| Abstract [eng] |
Results. As a result of RST, complete regression of all treated tumours was observed in 6 patients after two or more RST courses. A significant response – regression of more than 50% of all brain metastases and remission of the disease for over 6 months – was established in 14 patients. Partial response was observed in 16 patients with malignant brain tumours. For the rest of 18 patients the treatment was ineffective. The Karnofsky performance scale index increased immediately in 33 patients following RST treatment. RST was especially effective in the treatment of brain and bone metastatic lesions. As regards brain metastazes, in one patient all three brain metastatic lesions completely disappeared and there were no evidence of any recurrence in brain for 8 months. In 6 patients, regression of more than 50% of all brain metastases and remission of the disease for over 6 months was established. The median survival of 19 patients with multiplex brain metastases was 12 months from the moment of brain metastases detection. As regards bone metastazes, as a result of RST, all metastatic bone lesions completely disappeared in 7 patients. Conclusion. Radiosensitized advanced metastatic breast cancer treatment is a hopeful method, especially when lesions involve the brain and bones. |
| Published |
Vilnius : Vilniaus universiteto leidykla |
| Type |
Journal article |
| Language |
Lithuanian |
| Publication date |
2011 |
| CC license |
|
